SCHEMBL812702

SCHEMBL812702

CN(c1ccccc1)S(=O)(=O)c1ccccc1

nearest known ligand 0.78

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.78
CA9 Q16790 1/20 0.78
NR1I2 O75469 1/20 0.66
TSHR P16473 1/20 0.62
MAPT P10636 2/20 0.61
MCOLN3 Q8TDD5 1/20 0.61
NR1H3 Q13133 4/20 0.60
NR1H2 P55055 4/20 0.60
LMNA P02545 2/20 0.58
HTT P42858 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
PGR P06401 2/20 0.57
ATM Q13315 1/20 0.56
FFAR1 O14842 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3822617 0.88 CA12 (1.00) CA12CA9NR1I2TSHRMAPT
SCHEMBL11910521 0.88 CA12 (0.86) CA12CA9NR1I2MAPTMCOLN3
SCHEMBL6794824 0.88 CA12 (0.73) CA12CA9NR1I2TSHRMAPT
SCHEMBL5609715 0.86 CA12 (0.61) CA12CA9NR1I2TSHRMAPT
SCHEMBL693817 0.86 CA12 (0.66) CA12CA9NR1I2TSHRMAPT
SCHEMBL2690068 0.86 NR1I2 (0.61) CA12CA9NR1I2TSHRMAPT
SCHEMBL10186889 0.86 PGR (0.74) CA12CA9NR1I2MAPTMCOLN3
SCHEMBL3997987 0.86 NR1I2 (0.61) CA12CA9NR1I2TSHRMAPT
SCHEMBL14469933 0.86 FFAR1 (0.74) CA12CA9NR1I2TSHRMAPT
SCHEMBL7811989 0.86 CA12 (0.71) CA12CA9NR1I2TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107554018-B The preparation method of fire retarding polyurethane synthetic leather 福建禾欣中裕新材料有限公司 2019-03-15 CN claimed
EP-2969003-A1 METHODS AND COMPOSITIONS FOR BACTERIA INFECTIONS The University of Chicago (US) 2016-01-20 EP claimed
WO-2014144710-A1 METHODS AND COMPOSITIONS FOR BACTERIA INFECTIONS THE UNIVERSITY OF CHICAGO (US) 2014-09-18 WO claimed
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP claimed
US-20230288610-A1 WAVELENGTH SELECTIVE ABSORPTION FILTER AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-09-14 US disclosed
CN-108440345-B Preparation method of sulfonamide compound 西北师范大学 2020-11-24 CN disclosed
CN-108440345-A A kind of preparation method of sulfamide compound 西北师范大学 2018-08-24 CN disclosed
EP-2838533-B1 COMPOSITIONS AND METHODS OF MODULATING 15-PGDH ACTIVITY UNIV CASE WESTERN RESERVE (US) 2017-10-04 EP disclosed
US-9726932-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2017-08-08 US disclosed
US-9726932-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2017-08-08 US disclosed
US-9563075-B2 Method for manufacturing liquid crystal display device provided with front plate, and liquid crystal display device provided with front plate Konica Minolta, Inc. (JP) 2017-02-07 US disclosed
US-9563075-B2 Method for manufacturing liquid crystal display device provided with front plate, and liquid crystal display device provided with front plate Konica Minolta, Inc. (JP) 2017-02-07 US disclosed
US-6921740-B1 Electron-receiving compound and thermal recording material MITSUBISHI PAPER MIILS LTD. (JP) 2005-07-26 US disclosed
EP-1011652-A4 NOVEL DIARYLSULFONE NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS UNIV THE SCIENCES IN PHILADELP (US) 2004-12-22 EP disclosed
EP-0664321-B1 Polycarbonates stabilized against radiation BAYER AG (DE) 2003-04-16 EP disclosed
US-6303630-B1 TREATING HUMAN IMMUNODEFICIENCY VIRUS INFECTION BYADMINISTERING TO A HUMAN DIARYLSULFONE COMPOUND UNIVERSITY OF THE SCIENCES IN PHILADELPHIA 2001-10-16 US disclosed
EP-1011652-A1 NOVEL DIARYLSULFONE NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS University of the Sciences in Philadelphia (US) 2000-06-28 EP disclosed
US-6063790-A TREATMENT OF AIDS UNIVERSITY OF THE SCIENCES IN PHILADELPHIA (US) 2000-05-16 US disclosed
WO-1999006037-A1 NOVEL DIARYLSULFONE NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS UNIVERSITY OF THE SCIENCES IN PHILADELPHIA (US) 1999-02-11 WO disclosed
EP-0664321-A1 Polycarbonates stabilized against radiation BAYER AG (DE) 1995-07-26 EP disclosed