Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | KHK | P50053 | 1/20 | 0.37 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8125537 | 0.84 | CYP11B2 (0.51) | CYP11B2CYP11B1BRD4 | |
| SCHEMBL647782 | 0.80 | BCHE (0.46) | — | |
| SCHEMBL27334234 | 0.80 | CYP11B2 (0.37) | CYP11B2CYP11B1CYP1A2ALDH1A1TSHR | |
| SCHEMBL8125432 | 0.79 | TSHR (0.39) | CYP11B2CYP11B1TSHRKHKSUV39H1 | |
| SCHEMBL8132745 | 0.78 | KDM4E (0.46) | ALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL8129126 | 0.78 | TSHR (0.39) | CYP11B2CYP11B1TSHRKHKSUV39H1 | |
| SCHEMBL8127220 | 0.77 | HSD17B10 (0.38) | CYP1A2ALDH1A1HSD17B10CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL11094058 | 0.71 | KMT2A (0.59) | MEN1CYP2D6KMT2AMAOAKHK | |
| SCHEMBL5352956 | 0.71 | BRD4 (0.48) | CYP1A2ALDH1A1HSD17B10USP2CYP3A4 | |
| SCHEMBL8125646 | 0.70 | MEN1 (0.46) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664291-B1 | PYRIMIDINE COMPOUND | UBE INDUSTRIES (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5610303-A | MONOAMIDE OXIDASE INHIBITORS | UBE INDUSTRIES, LTD. (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0664291-A1 | PYRIMIDINE COMPOUND | UBE INDUSTRIES, LTD. (JP) | 1995-07-26 | — | — | EP | disclosed |