Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127544 | 0.90 | POLB (0.43) | CD274KDM4EPDCD1NPSR1POLB | |
| SCHEMBL8123365 | 0.83 | MEN1 (0.45) | MEN1KMT2ACD274KDM4EALDH1A1 | |
| SCHEMBL6960955 | 0.77 | F2 (0.42) | MEN1KMT2AF2CD274KDM4E | |
| SCHEMBL7820796 | 0.77 | HPGD (0.44) | MEN1KMT2AF2CD274KDM4E | |
| SCHEMBL6598179 | 0.76 | F2 (0.72) | MEN1KMT2AF2ALDH1A1LMNA | |
| SCHEMBL6598173 | 0.76 | F2 (0.72) | MEN1KMT2AF2ALDH1A1LMNA | |
| SCHEMBL7831868 | 0.74 | F2 (0.41) | MEN1KMT2AF2KDM4EALDH1A1 | |
| SCHEMBL7348255 | 0.72 | KDM4E (0.41) | MEN1KMT2AF2KDM4EALDH1A1 | |
| SCHEMBL6598137 | 0.72 | F2 (0.61) | F2POLB | |
| SCHEMBL6598135 | 0.72 | F2 (0.61) | F2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980366-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2000-05-17 | — | — | EP | disclosed |
| EP-0980366-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049160-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |