Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LTA4H | P09960 | 3/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831868 | 0.82 | F2 (0.41) | F2KMT2AMEN1SMN1; SMN2TDP1 | |
| SCHEMBL8128012 | 0.77 | MEN1 (0.39) | F2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6967074 | 0.77 | F2 (0.56) | F2ESR1ESR2HRH3 | |
| SCHEMBL7820796 | 0.77 | HPGD (0.44) | F2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7445212 | 0.77 | F2 (0.46) | F2KMT2AMEN1SMN1; SMN2TDP1 | |
| SCHEMBL8123365 | 0.77 | MEN1 (0.45) | KMT2AMEN1TDP1KDM4EALDH1A1 | |
| SCHEMBL7347611 | 0.75 | LTA4H (0.42) | F2KMT2AMEN1ESR1ESR2 | |
| SCHEMBL7348255 | 0.75 | KDM4E (0.41) | F2KMT2AMEN1TDP1KDM4E | |
| SCHEMBL7441910 | 0.74 | F2 (0.49) | F2ESR1LTA4HTSHRHTT | |
| SCHEMBL7819938 | 0.73 | F2 (0.37) | F2KDM4EMAPK1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980367-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-0980367-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049161-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |