Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | CDK4 | P11802 | 2/20 | 0.49 |
| ▸ | CCND1 | P24385 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18301162 | 0.83 | HTR2A (0.54) | HTR2AHTR2CCDK4CCND1RAB9A | |
| SCHEMBL9178579 | 0.81 | HTR2A (0.53) | HTR2AHTR2CCDK4CCND1RAB9A | |
| SCHEMBL8121319 | 0.78 | HTR2C (0.55) | HTR2AHTR2CPRMT5HTR7 | |
| SCHEMBL8959527 | 0.78 | HTR2A (0.59) | HTR2AHTR2CCDK4CCND1KMO | |
| SCHEMBL8959910 | 0.78 | HTR2A (0.55) | HTR2AHTR2CCDK4CCND1KMO | |
| SCHEMBL18856964 | 0.78 | HTR2A (0.59) | HTR2AHTR2CCDK4CCND1KMO | |
| SCHEMBL18856961 | 0.78 | HTR2A (0.58) | HTR2AHTR2CCDK4CCND1KMO | |
| Hydrochloric Acid SCHEMBL29902400 | 0.77 | HTR2A (0.58) | HTR2AHTR2CCDK4CCND1KMO | |
| Hydrochloric Acid SCHEMBL27171474 | 0.77 | HTR2A (0.58) | HTR2AHTR2CCDK4CCND1KMO | |
| SCHEMBL29379279 | 0.76 | CDK4 (0.68) | HTR2AHTR2CCDK4CCND1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642513-B1 | INDOLOCARBAZOLE IMIDES AND THEIR USE | KTB TUMORFORSCHUNGSGESELLSCHAF (DE) | 2000-08-09 | — | — | EP | disclosed |
| US-5945440-A | Indolocarbazole imides and the use thereof | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1999-08-31 | — | — | US | disclosed |
| US-5883114-A | TREATING CANCEROUS TUMORS, INFLAMMATORY DISEASES, AND ALLERGIES | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | disclosed |
| EP-0642513-A1 | INDOLOCARBAZOLE IMIDES AND THEIR USE | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1995-03-15 | — | — | EP | disclosed |
| WO-1993024491-A1 | INDOLOCARBAZOLE IMIDES AND THEIR USE | Gödecke Aktiengesellschaft (DE) | 1993-12-09 | — | — | WO | disclosed |