Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 4/20 | 0.61 |
| ▸ | GSK3B | P49841 | 4/20 | 0.61 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.57 |
| ▸ | CDK4 | P11802 | 2/20 | 0.57 |
| ▸ | CCND1 | P24385 | 2/20 | 0.57 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.57 |
| ▸ | CDK2 | P24941 | 2/20 | 0.57 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | PRKACA | P17612 | 1/20 | 0.56 |
| ▸ | PRKACG | P22612 | 1/20 | 0.56 |
| ▸ | PRKACB | P22694 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8161651 | 0.85 | GSK3B (0.80) | PRKCAGSK3BCCNE2CDK4CCND1 | |
| SCHEMBL8120702 | 0.84 | PRKCA (0.80) | PRKCAGSK3BPRKD1TDP1CCNE2 | |
| SCHEMBL14041601 | 0.82 | GSK3B (0.66) | PRKCAGSK3BPIM1PRKACAPRKACG | |
| SCHEMBL30834694 | 0.82 | PRKCA (0.64) | PRKCAGSK3BCCNE2CDK4CCND1 | |
| SCHEMBL8122419 | 0.82 | CCNT1 (0.66) | PRKCAGSK3BPRKD1TDP1CDK2 | |
| SCHEMBL8127999 | 0.82 | CCNT1 (0.66) | PRKCAGSK3BPRKD1TDP1CDK2 | |
| SCHEMBL8122774 | 0.81 | PRKCA (0.63) | PRKCAGSK3BPRKD1TDP1CDK2 | |
| SCHEMBL8113347 | 0.81 | PRKCA (0.63) | PRKCAGSK3BPRKD1TDP1CDK2 | |
| SCHEMBL8075384 | 0.80 | PRKCA (0.61) | PRKCAGSK3BPIM1 | |
| SCHEMBL7502631 | 0.80 | GSK3B (0.70) | PRKCAGSK3BCCNE2CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642513-B1 | INDOLOCARBAZOLE IMIDES AND THEIR USE | KTB TUMORFORSCHUNGSGESELLSCHAF (DE) | 2000-08-09 | — | — | EP | disclosed |
| EP-0642513-A1 | INDOLOCARBAZOLE IMIDES AND THEIR USE | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1995-03-15 | — | — | EP | disclosed |
| WO-1993024491-A1 | INDOLOCARBAZOLE IMIDES AND THEIR USE | Gödecke Aktiengesellschaft (DE) | 1993-12-09 | — | — | WO | disclosed |