Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | PNMT | P11086 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20162398 | 0.89 | GRIN1 (0.54) | ATAD2CYP1A2GRIN1GRIN2BCYP11B1 | |
| SCHEMBL10152051 | 0.89 | GRIN1 (0.50) | ATAD2CYP1A2GRIN1GRIN2BCYP11B1 | |
| SCHEMBL4106672 | 0.87 | GAA (0.53) | ATAD2CYP1A2GRIN1GRIN2BSIRT2 | |
| SCHEMBL14049826 | 0.87 | GRIN1 (0.57) | ATAD2GRIN1GRIN2BSIRT2CASP6 | |
| SCHEMBL18421287 | 0.86 | GRIN1 (0.52) | ATAD2CYP1A2GRIN1GRIN2BCYP11B1 | |
| SCHEMBL18421420 | 0.85 | GRIN1 (0.51) | ATAD2GRIN1GRIN2BSIRT2CASP6 | |
| SCHEMBL2676069 | 0.84 | SIRT2 (0.51) | ATAD2GRIN1GRIN2BSIRT2CASP6 | |
| SCHEMBL2675072 | 0.83 | NOS3 (0.49) | ATAD2GRIN1GRIN2BSIRT2CASP6 | |
| SCHEMBL2675597 | 0.83 | GRIN1 (0.51) | ATAD2GRIN1GRIN2BSIRT2CASP6 | |
| SCHEMBL18422001 | 0.82 | GRIN2B (0.47) | ATAD2GRIN1GRIN2BSIRT2CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049692-A1 | NOVEL BICYCLENE-SUBSTITUTED OXAZOLIDINONES | Bayer Aktiengesellschaft (DE) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999037641-A1 | NOVEL BICYCLENE-SUBSTITUTED OXAZOLIDINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-07-29 | — | — | WO | disclosed |