Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.86 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.86 |
| ▸ | ESR1 | P03372 | 4/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.32 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.32 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.32 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL561726 | 1.00 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL9420677 | 1.00 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL3181354 | 1.00 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL1951204 | 1.00 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL5909610 | 0.97 | TDP1 (0.80) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL5692052 | 0.97 | TDP1 (0.80) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Oxygen SCHEMBL11268842 | 0.94 | TDP1 (0.75) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL101 | 0.93 | TDP1 (1.00) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Benzene SCHEMBL6890099 | 0.93 | TDP1 (1.00) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL5028587 | 0.93 | TDP1 (1.00) | TDP1CYP3A4ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3542 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206588-A | 8-Hydroxyquinoline-triphenylphosphine rhodium (III) complex, synthesis method and application thereof | 玉林师范学院 | 2024-06-18 | — | — | CN | claimed |
| CN-118204074-A | Cyclic ether MOF stabilized solitary atom catalyst and preparation and application thereof | 中国科学院大连化学物理研究所 | 2024-06-18 | — | — | CN | claimed |
| CN-117776887-A | Preparation method of cyclopropyl methyl ketone | 浙江大学 | 2024-03-29 | — | — | CN | claimed |
| CN-114634407-B | Method for stereospecifically synthesizing 2-enal, 2-enone compound and deuterated compound thereof | 复旦大学 | 2024-02-02 | — | — | CN | claimed |
| CN-117343330-A | Phenyl silicone resin containing branched structure and preparation method and application thereof | 万华化学集团股份有限公司 | 2024-01-05 | — | — | CN | claimed |
| US-11767286-B2 | Phenylpropionate compound, preparation method for same, and applications thereof | SUZHOU PHARMAVAN CO., LTD (CN) | 2023-09-26 | — | — | US | claimed |
| CN-110540608-B | Method for preparing hydrogenated diene based nanoemulsions and use of gemini surfactants | 王辉 | 2022-12-23 | — | — | CN | claimed |
| CN-109719304-B | Method for preparing noble metal lone atoms in solution and application | 中国科学院大连化学物理研究所 | 2022-08-09 | — | — | CN | claimed |
| CN-114829367-A | Functionalization of 1, 3-alpha-dienes (I) | 帝斯曼知识产权资产管理有限公司 | 2022-07-29 | — | — | CN | claimed |
| US-20220227719-A1 | A diphenylamine-linked chiral bis(oxazoline) ligand without C2-symmetry, synthesis method and application thereof | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2022-07-21 | — | — | US | claimed |
| US-4550096-A | Homogeneous catalytic system comprising rhodium, hydrazine and phosphine and a process for the preparation of same | PLURICHEMIE ANSTALT (LI) | 1985-10-29 | — | — | US | claimed |
| US-4500458-A | CATALYST FROM RHODIUM SALT OR A COMPLEX WITH A HYDRAZINE | PLURICHEMIE ANSTALT (LI) | 1985-02-19 | — | — | US | claimed |
| US-4477443-A | INCREASED ANTIBIOTIC ACTIVITY | Zaidan Hojin Biselbutsu Kagaku Kenkyu Kai (Microbial Chemistry Research Foundation) (JP) | 1984-10-16 | — | — | US | claimed |
| EP-0086046-A1 | A process for the preparation of alpha-6-DEOXYTETRACYCLINES | PLURICHEMIE ANSTALT (LI) | 1983-08-17 | — | — | EP | claimed |
| EP-0070170-A1 | Tylosin derivatives, their preparation and pharmaceutical compositions containing them | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1983-01-19 | — | — | EP | claimed |
| EP-0059616-A1 | Removal of metal catalysts from process streams | MERCK & CO. INC. (US) | 1982-09-08 | — | — | EP | claimed |
| US-4194056-A | Acetic acid from methyl formate | CHEVRON RESEARCH COMPANY (US) | 1980-03-18 | — | — | US | claimed |
| US-4111952-A | Process for preparing lower lactams from allylic amine substrates | TEXACO INC. (US) | 1978-09-05 | — | — | US | claimed |
| US-4107079-A | NOBLE METAL COORDINATION COMPLEX | RHONE-POULENC INDUSTRIES (FR) | 1978-08-15 | — | — | US | claimed |
| US-3993672-A | TO FORM EPOXIDE AND ALLYL ALCOHOL, CATALYSIS | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) | 1976-11-23 | — | — | US | claimed |