Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | HTR2C | P28335 | 3/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 4/20 | 0.44 |
| ▸ | BPTF | Q12830 | 4/20 | 0.43 |
| ▸ | NOS3 | P29474 | 3/20 | 0.43 |
| ▸ | NOS1 | P29475 | 3/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23956097 | 0.91 | HTR2C (0.67) | HTR2AHTR2CHDAC3HDAC1HDAC2 | |
| SCHEMBL8127772 | 0.82 | HTR2C (0.68) | HTR2AHTR2CHDAC3HDAC1HDAC2 | |
| SCHEMBL6870435 | 0.78 | HDAC3 (0.48) | HTR2AHTR2CHDAC3HDAC1HDAC2 | |
| SCHEMBL6928247 | 0.75 | PRKCI (0.51) | HTR2AHTR2CHTR1DBPTFNOS3 | |
| SCHEMBL7253554 | 0.75 | HTR2A (0.54) | HTR2AHTR2CHTR1DBPTFNOS3 | |
| SCHEMBL8113042 | 0.75 | HDAC3 (0.41) | HTR2AHTR2CHDAC3HDAC1HDAC2 | |
| SCHEMBL16741930 | 0.75 | EGFR (0.53) | HTR2AHTR2CBPTFNOS3NOS1 | |
| SCHEMBL23956099 | 0.74 | HTR2C (0.61) | HTR2AHTR2CHTR1DNOS3NOS1 | |
| SCHEMBL23927851 | 0.73 | HTR2C (0.47) | HTR2AHTR2C | |
| SCHEMBL24110335 | 0.73 | HTR2C (0.40) | HTR2AHTR2CHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642513-B1 | INDOLOCARBAZOLE IMIDES AND THEIR USE | KTB TUMORFORSCHUNGSGESELLSCHAF (DE) | 2000-08-09 | — | — | EP | disclosed |
| US-5945440-A | Indolocarbazole imides and the use thereof | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1999-08-31 | — | — | US | disclosed |
| US-5883114-A | TREATING CANCEROUS TUMORS, INFLAMMATORY DISEASES, AND ALLERGIES | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | disclosed |
| EP-0642513-A1 | INDOLOCARBAZOLE IMIDES AND THEIR USE | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1995-03-15 | — | — | EP | disclosed |
| WO-1993024491-A1 | INDOLOCARBAZOLE IMIDES AND THEIR USE | Gödecke Aktiengesellschaft (DE) | 1993-12-09 | — | — | WO | disclosed |