Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.46 |
| ▸ | NAAA | Q02083 | 2/20 | 0.46 |
| ▸ | RRM1 | P23921 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.45 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243056 | 1.00 | METAP2 (0.46) | METAP2EPHX1NAAARRM1DPP7 | |
| SCHEMBL21457850 | 1.00 | METAP2 (0.46) | METAP2EPHX1NAAARRM1DPP7 | |
| SCHEMBL8328041 | 1.00 | METAP2 (0.46) | METAP2EPHX1NAAARRM1DPP7 | |
| SCHEMBL11251763 | 0.94 | DPP7 (0.40) | METAP2EPHX1NAAARRM1DPP7 | |
| SCHEMBL9150255 | 0.88 | EPHX1 (0.57) | METAP2EPHX1NAAARRM1DPP7 | |
| SCHEMBL22618594 | 0.88 | EPHX1 (0.57) | METAP2EPHX1NAAARRM1DPP7 | |
| SCHEMBL9154760 | 0.88 | EPHX1 (0.57) | METAP2EPHX1NAAARRM1DPP7 | |
| SCHEMBL12354358 | 0.87 | DPP7 (0.56) | METAP2EPHX1NAAARRM1DPP7 | |
| SCHEMBL20875992 | 0.82 | FNTA (0.54) | METAP2EPHX1NAAARRM1DPP7 | |
| SCHEMBL20875820 | 0.82 | FNTA (0.54) | METAP2EPHX1NAAARRM1DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816375-A1 | GLYCOCONJUGATES OF OPIATED SUBSTANCES | ROLABO SL (ES) | 1998-01-07 | — | — | EP | claimed |
| EP-0984974-A1 | GLYCOCONJUGATES OF OPIATED SUBSTANCES | ROLABO S.L. (ES) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998054196-A1 | GLYCOCONJUGATES OF OPIATED SUBSTANCES | ROLABO SL (ES) | 1998-12-03 | — | — | WO | disclosed |
| EP-0816375-A1 | GLYCOCONJUGATES OF OPIATED SUBSTANCES | ROLABO SL (ES) | 1998-01-07 | — | — | EP | disclosed |