Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738115 | 0.79 | TDP1 (0.42) | TDP1CYP3A4TSHRHSD17B10ALOX15 | |
| SCHEMBL11677131 | 0.77 | MAPT (0.33) | TDP1ALDH1A1L3MBTL1CA2CA4 | |
| SCHEMBL8122769 | 0.74 | TDP1 (0.36) | TDP1CYP3A4TSHRHSD17B10ALOX15 | |
| SCHEMBL3803700 | 0.73 | TDP1 (0.45) | TDP1CYP3A4TSHRHSD17B10ALOX15 | |
| SCHEMBL27503034 | 0.71 | TSHR (0.43) | TDP1CYP3A4TSHRHSD17B10ALOX15 | |
| SCHEMBL28973883 | 0.69 | TDP1 (0.41) | TDP1CYP3A4TSHRHSD17B10ALOX15 | |
| SCHEMBL301662 | 0.69 | HSD17B10 (0.59) | TDP1CYP3A4TSHRHSD17B10ALOX15 | |
| SCHEMBL11451272 | 0.67 | TSHR (0.39) | TDP1CYP3A4TSHRHSD17B10ALOX15 | |
| SCHEMBL94118 | 0.67 | KLK1 (0.45) | TDP1CYP3A4TSHRHSD17B10ALOX15 | |
| SCHEMBL457449 | 0.67 | TDP1 (0.39) | TDP1CYP3A4TSHRHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-52028539-A | — | — | None | — | — | JP | disclosed |
| US-6103891-A | Method for the synthesis of nucleotide or oligonucleotide phosphoramidites | ISIS PHARMACEUTICALS, INC. (US) | 2000-08-15 | — | — | US | disclosed |
| JP-S5228539-A | NEW FLAME RETARDER OF ORGANIC PHOSPHOROUS ESTER | KAWAGUCHI KAGAKU KOGYO KK | 1977-03-03 | — | — | JP | disclosed |
| US-3966697-A | CATALYST OF COBALT COMPOUND, ORGANOALUMINUM HALIDE, PHOSPHITE, H-ACIDIC COMPOUND | CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |