Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8129030 | 0.77 | TDP1 (0.39) | MAPTL3MBTL1CA2CA4ALDH1A1 | |
| SCHEMBL5014092 | 0.72 | RAPGEF4 (0.38) | MAPTKDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL3683983 | 0.72 | CA2 (0.54) | MAPTL3MBTL1CA2CA4KDM4E | |
| SCHEMBL10766331 | 0.68 | KMT2A (0.42) | MAPTL3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL5085895 | 0.67 | MAPT (0.51) | MAPTL3MBTL1CA2CA4KDM4E | |
| SCHEMBL31540293 | 0.67 | ACHE (0.65) | MAPTL3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL24086743 | 0.65 | CA2 (0.46) | MAPTL3MBTL1CA2CA4KDM4E | |
| SCHEMBL1159937 | 0.65 | SMN1; SMN2 (0.48) | CA2ALDH1A1TDP1 | |
| SCHEMBL11572063 | 0.65 | ALDH1A1 (0.52) | MAPTL3MBTL1CA2CA4KDM4E | |
| SCHEMBL9880773 | 0.65 | ACHE (0.70) | MAPTL3MBTL1CA2CA4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4012399-A | ULTRAVIOLET LIGHT ABSORBERS AND STABILIZERS | CINCINNATI MILACRON CHEMICALS, INC. (US) | 1977-03-15 | — | — | US | disclosed |
| US-3959220-A | Polymer additives comprising transition metal complexes with trivalent phosphorous compounds | CINCINNATI MILACRON CHEMICALS, INC. (US) | 1976-05-25 | — | — | US | disclosed |