Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 10/20 | 0.35 |
| ▸ | IKBKB | O14920 | 3/20 | 0.33 |
| ▸ | RARA | P10276 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959705 | 0.88 | F2 (0.41) | F2ELANERARGIKBKBRARA | |
| SCHEMBL8128464 | 0.84 | FABP4 (0.38) | F2ELANERARGIKBKBRARA | |
| SCHEMBL7962553 | 0.78 | RARG (0.36) | F2ELANERARGIKBKBRARA | |
| SCHEMBL8127905 | 0.77 | PTPN1 (0.44) | F2ELANERARGIKBKBRARA | |
| SCHEMBL8132737 | 0.77 | RARG (0.38) | F2ELANERARGCTNNB1KDM4E | |
| SCHEMBL8134415 | 0.76 | RARG (0.35) | F2ELANERARGIKBKBRARA | |
| SCHEMBL7962775 | 0.76 | F2 (0.49) | F2ELANERARGRARARARB | |
| SCHEMBL7962550 | 0.75 | PTPN1 (0.36) | F2ELANERARGIKBKBRARA | |
| SCHEMBL8129345 | 0.74 | F2 (0.37) | F2ELANERARGIKBKBRARA | |
| SCHEMBL7962776 | 0.73 | FABP4 (0.38) | F2ELANERARGIKBKBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994708-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | Merck & Co., Inc. (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1998055123-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 1998-12-10 | — | — | WO | disclosed |