Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.63 |
| ▸ | HEXA | P06865 | 9/20 | 0.56 |
| ▸ | HEXB | P07686 | 9/20 | 0.56 |
| ▸ | OGA | O60502 | 1/20 | 0.56 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8138008 | 0.95 | HEXA (0.58) | SIRT1HEXAHEXBOGATERT | |
| SCHEMBL7982472 | 0.93 | SIRT1 (0.55) | SIRT1HEXAHEXBOGATERT | |
| SCHEMBL5953603 | 0.91 | SIRT1 (0.59) | SIRT1HEXAHEXBOGATERT | |
| SCHEMBL7982362 | 0.88 | HEXA (0.51) | SIRT1HEXAHEXBOGATERT | |
| SCHEMBL8129861 | 0.81 | HEXA (0.55) | SIRT1HEXAHEXBOGADYRK3 | |
| SCHEMBL8134515 | 0.80 | SIRT1 (0.48) | SIRT1HEXAHEXBOGATERT | |
| SCHEMBL8129260 | 0.80 | SIRT1 (0.50) | SIRT1HEXAHEXBOGATERT | |
| SCHEMBL8133497 | 0.79 | SIRT1 (0.49) | SIRT1HEXAHEXBOGATERT | |
| SCHEMBL8125966 | 0.79 | SIRT1 (0.49) | SIRT1HEXAHEXBOGATERT | |
| SCHEMBL8131634 | 0.79 | SIRT1 (0.49) | SIRT1HEXAHEXBOGATERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820985-B1 | Bis imide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-08-30 | — | — | EP | disclosed |
| EP-0820985-A1 | Bis imide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-01-28 | — | — | EP | disclosed |