Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.35 |
| ▸ | CTSH | P09668 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127763 | 0.90 | CTSK (0.36) | CTSKDPP8DPP7DPP4DPP9 | |
| SCHEMBL8121587 | 0.87 | CTSK (0.40) | CTSKDPP8DPP7DPP4DPP9 | |
| SCHEMBL8127680 | 0.82 | SLC7A5 (0.37) | CTSKDPP4 | |
| SCHEMBL28506993 | 0.79 | CTSK (0.42) | CTSKSLC15A1TSHRSMN1; SMN2CA1 | |
| SCHEMBL8130196 | 0.79 | SLC7A5 (0.37) | DPP4TSHR | |
| SCHEMBL24786197 | 0.78 | DPP7 (0.43) | CTSKDPP8DPP7DPP4DPP9 | |
| SCHEMBL8129257 | 0.78 | DPP7 (0.43) | CTSKDPP8DPP7DPP4DPP9 | |
| SCHEMBL19447199 | 0.78 | CTSK (0.42) | CTSKSLC15A1ABCB1TSHRSMN1; SMN2 | |
| SCHEMBL27193080 | 0.78 | DPP7 (0.43) | CTSKDPP8DPP7DPP4DPP9 | |
| SCHEMBL6384307 | 0.77 | CTSK (0.44) | CTSKTSHRSMN1; SMN2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054891-A1 | PRODRUGS | MEDIVIR AB (SE) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999041275-A1 | PRODRUGS | MEDIVIR AB (SE) | 1999-08-19 | — | — | WO | disclosed |