Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.68 |
| ▸ | FABP3 | P05413 | 6/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Ethylhexanoic Acid SCHEMBL29893966 | 0.95 | CA2 (0.70) | CA2FABP3NFKB1GPR84MAPK1 | |
| Stearic Acid SCHEMBL8665090 | 0.95 | CA2 (0.70) | CA2FABP3NFKB1GPR84MAPK1 | |
| 2-Ethylhexanoic Acid SCHEMBL9222984 | 0.95 | CA2 (0.76) | CA2FABP3NFKB1GPR84MAPK1 | |
| 2-Ethylhexanoic Acid SCHEMBL31503113 | 0.95 | CA2 (0.70) | CA2FABP3NFKB1GPR84MAPK1 | |
| Stearic Acid SCHEMBL17707712 | 0.95 | CA2 (0.70) | CA2FABP3NFKB1GPR84MAPK1 | |
| Sebacic Acid SCHEMBL8747721 | 0.93 | CA2 (0.72) | CA2FABP3NFKB1GPR84MAPK1 | |
| 2-Ethylhexanoic Acid SCHEMBL6328306 | 0.93 | CA2 (0.72) | CA2FABP3NFKB1GPR84MAPK1 | |
| 2-Ethylhexanoic Acid SCHEMBL11336103 | 0.92 | CA2 (0.70) | CA2FABP3NFKB1GPR84MAPK1 | |
| 2-Ethylhexanoic Acid SCHEMBL5486006 | 0.88 | CA2 (0.88) | CA2NFKB1MAPK1CA1 | |
| Oleic Acid SCHEMBL10522023 | 0.86 | FABP3 (0.69) | CA2FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020405-A | MIXTURE CONTAINING REVERSIBLY CROSSLINKED POLYMER | WESTVACO CORPORATION (US) | 2000-02-01 | — | — | US | claimed |
| US-6007610-A | COMPRISING A REVERSIBLY-CROSSLINKED THIXOTROPIC POLYMER AND A COLORANT ON A SUBSTRATE WITH A RECORDING DEVICE OF INK-CONTACTING METAL CONSTRUCTION; MADE BY HEATING THE POLYMER AND CROSSLINKER, STIRRING, HOMOGENIZING; ADDING COLOR | WESTVACO CORPORATION (US) | 1999-12-28 | — | — | US | claimed |
| US-6001904-A | COLORS AND REVERSE CROSSLINKED POLYMER WITH CROSSLINKING AGENTS | WESTVACO CORPORATION (US) | 1999-12-14 | — | — | US | claimed |
| US-5973036-A | QUALITY IMAGES, SCRATCH RESISTANCE, ABRASION RESISTANCE, LOW-TEMPERATURE STORAGE STABILITY AND FLEXIBILITY, OFFSET AND PICK RESISTANCE, ADHESION, CORROSION RESISTANCE | WESTVACO CORPORATION (US) | 1999-10-26 | — | — | US | claimed |