Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 10/20 | 0.44 |
| ▸ | HTR2A | P28223 | 8/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR1D | P28221 | 2/20 | 0.42 |
| ▸ | HTR1B | P28222 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 4/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8128490 | 0.89 | SLC2A1 (0.66) | SLC2A1NPC1RAB9AHTR2CHTR2A | |
| SCHEMBL8122610 | 0.86 | SLC2A1 (0.64) | SLC2A1NPC1RAB9AHTR2CHTR2A | |
| SCHEMBL8120361 | 0.86 | SLC2A1 (0.74) | SLC2A1NPC1RAB9AHTR2CHTR2A | |
| SCHEMBL8130315 | 0.86 | SLC2A1 (0.71) | SLC2A1NPC1RAB9AHTR2CHTR2A | |
| SCHEMBL8134765 | 0.85 | SLC2A1 (0.64) | SLC2A1NPC1RAB9AHTR2CHTR2A | |
| SCHEMBL8131252 | 0.84 | SLC2A1 (0.70) | SLC2A1NPC1RAB9AHTR2CHTR2A | |
| SCHEMBL8120540 | 0.84 | SLC2A1 (0.68) | SLC2A1NPC1RAB9AHTR2CHTR2A | |
| SCHEMBL8121339 | 0.83 | SLC2A1 (0.67) | SLC2A1NPC1RAB9AHTR2CHTR2A | |
| SCHEMBL8126725 | 0.82 | SLC2A1 (0.68) | SLC2A1NPC1RAB9AHTR2CHTR2A | |
| SCHEMBL8142686 | 0.81 | SLC2A1 (0.70) | SLC2A1NPC1RAB9AHTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975593-A1 | INDOLE DERIVATIVES HAVING COMBINED 5HT1A, 5HT1B AND 5HT1D RECEPTOR ANTAGONIST ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998050358-A1 | INDOLE DERIVATIVES HAVING COMBINED 5HT1A, 5HT1B AND 5HT1D RECEPTOR ANTAGONIST ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | disclosed |