Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.44 |
| ▸ | RAF1 | P04049 | 3/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | ESRRA | P11474 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1129534 | 0.83 | MEN1 (0.44) | ARRAF1MEN1LMNAMAPT | |
| SCHEMBL14645467 | 0.81 | AR (0.60) | ARRAF1 | |
| SCHEMBL1282625 | 0.81 | AR (0.49) | AR | |
| SCHEMBL29741891 | 0.81 | AR (0.60) | ARRAF1 | |
| SCHEMBL2396132 | 0.80 | AR (0.51) | ARRAF1 | |
| SCHEMBL28020121 | 0.80 | AR (0.44) | ARRAF1MEN1MAPTKMT2A | |
| SCHEMBL2749921 | 0.78 | MAPT (0.34) | ARMEN1MAPTKMT2A | |
| SCHEMBL1283210 | 0.78 | AR (0.42) | AR | |
| SCHEMBL8125844 | 0.78 | AR (0.48) | ARESRRA | |
| SCHEMBL17555023 | 0.75 | TEAD1 (0.48) | ARMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028945-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS ANTI-INFLAMMATORY AGENTS | Amgen Inc. (US) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999024404-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS ANTI-INFLAMMATORY AGENTS | AMGEN INC. (US) | 1999-05-20 | — | — | WO | disclosed |