SCHEMBL28020121

SCHEMBL28020121

Nc1ccc(Oc2cc[c]cc2)cc1C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 11/20 0.44
NR4A1 P22736 1/20 0.42
FFAR4 Q5NUL3 2/20 0.38
HDAC3 O15379 2/20 0.36
BRAF P15056 2/20 0.36
HDAC4 P56524 2/20 0.36
HDAC1 Q13547 2/20 0.36
HDAC7 Q8WUI4 2/20 0.36
HDAC2 Q92769 2/20 0.36
HDAC10 Q969S8 2/20 0.36
HDAC11 Q96DB2 2/20 0.36
HDAC8 Q9BY41 2/20 0.36
HDAC6 Q9UBN7 2/20 0.36
HDAC9 Q9UKV0 2/20 0.36
HDAC5 Q9UQL6 2/20 0.36
RAB9A P51151 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MEN1 O00255 1/20 0.35
MITF O75030 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8146457 0.89 NR4A1 (0.52) ARNR4A1FFAR4HDAC3BRAF
SCHEMBL710315 0.88 NR4A1 (0.54) ARNR4A1FFAR4HDAC3BRAF
SCHEMBL649034 0.84 NR4A1 (0.47) ARNR4A1FFAR4HDAC3BRAF
SCHEMBL30287636 0.84 NR4A1 (0.47) ARNR4A1FFAR4HDAC3BRAF
SCHEMBL29896686 0.84 ALDH1A1 (0.52) ARNR4A1FFAR4RAB9AMEN1
SCHEMBL7190049 0.84 ALDH1A1 (0.52) ARNR4A1FFAR4RAB9AMEN1
SCHEMBL30287666 0.83 MAOB (0.48) ARNR4A1FFAR4RAB9AMEN1
SCHEMBL21332700 0.83 SCN9A (0.47) ARNR4A1FFAR4HDAC3BRAF
SCHEMBL10664109 0.83 MAOB (0.48) ARNR4A1FFAR4RAB9AMEN1
SCHEMBL5583842 0.81 AR (0.60) ARNR4A1FFAR4RAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105176078-A Electroplating biphenyl type maleimido polyimide modified engineering plastic alloy and preparation method thereof NAT UNIV DONG HWA 2015-12-23 CN claimed
CN-105153693-A Platable MPI (polyimide film with maleimide side groups) modified engineering plastic alloy and preparation method thereof NAT UNIV DONG HWA 2015-12-16 CN claimed
CN-105153692-A Platable PA66-PPO-MPI (polyamide 66-polyphenylene oxide-polyimide film with maleimide side groups) engineering plastic alloy and preparation method thereof NAT UNIV DONG HWA 2015-12-16 CN claimed
CN-105086419-A Fluorine-contained polyimide modified engineering plastic alloy capable of being electroplated and preparation method thereof NAT UNIV DONG HWA 2015-11-25 CN claimed
CN-104760369-A Fluorine-containing polyimide copper-clad plate and preparation method thereof NAT UNIV DONG HWA 2015-07-08 CN claimed
CN-105176078-A Electroplating biphenyl type maleimido polyimide modified engineering plastic alloy and preparation method thereof NAT UNIV DONG HWA 2015-12-23 CN disclosed
CN-105153693-A Platable MPI (polyimide film with maleimide side groups) modified engineering plastic alloy and preparation method thereof NAT UNIV DONG HWA 2015-12-16 CN disclosed
CN-105153692-A Platable PA66-PPO-MPI (polyamide 66-polyphenylene oxide-polyimide film with maleimide side groups) engineering plastic alloy and preparation method thereof NAT UNIV DONG HWA 2015-12-16 CN disclosed
CN-105086419-A Fluorine-contained polyimide modified engineering plastic alloy capable of being electroplated and preparation method thereof NAT UNIV DONG HWA 2015-11-25 CN disclosed
CN-104760369-A Fluorine-containing polyimide copper-clad plate and preparation method thereof NAT UNIV DONG HWA 2015-07-08 CN disclosed