⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2452646 | 1.00 | — | — | |
| SCHEMBL25140620 | 0.79 | — | — | |
| SCHEMBL15589125 | 0.74 | — | — | |
| SCHEMBL9906143 | 0.74 | DNM1 (0.60) | — | |
| SCHEMBL19919976 | 0.72 | — | — | |
| SCHEMBL9877397 | 0.72 | DNM1 (0.30) | — | |
| SCHEMBL10364721 | 0.69 | — | — | |
| SCHEMBL24774354 | 0.69 | CA12 (0.35) | — | |
| SCHEMBL26256008 | 0.69 | — | — | |
| SCHEMBL649261 | 0.69 | CA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427765-B1 | ALKOXY-4(1H)-PYRIDONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USE AS DRUGS | GOEDECKE AG (DE) | 2000-01-05 | — | — | EP | claimed |
| US-5185352-A | Treating or preventing cardiovascular disorders | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1993-02-09 | — | — | US | claimed |
| US-5322844-A | Cardiovascular disorders, antiinflammatory agents, antiallergens | GODECKE AKTIENGESELLSCHAFT (DE) | 1994-06-21 | — | — | US | disclosed |
| US-5185352-A | Treating or preventing cardiovascular disorders | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1993-02-09 | — | — | US | disclosed |