Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 11/20 | 0.38 |
| ▸ | ACE | P12821 | 6/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768922 | 0.84 | GAA (0.56) | GAAMAPTPTPN7MMEACE | |
| SCHEMBL5265048 | 0.81 | GAA (0.41) | GAAMAPTMMEACESMYD3 | |
| SCHEMBL8143867 | 0.78 | CYP1A2 (0.39) | GAAMAPTPTPN7MMEDRD2 | |
| SCHEMBL6195716 | 0.75 | ALDH1A1 (0.46) | GAAMAPTPTPN7MMEACE | |
| SCHEMBL1531662 | 0.73 | GAA (0.69) | GAAMAPTMMEACESMYD3 | |
| SCHEMBL10841161 | 0.73 | ALDH1A1 (0.39) | DRD2DRD3 | |
| SCHEMBL1150614 | 0.73 | GAA (0.69) | GAAMAPTMMEACESMYD3 | |
| SCHEMBL444953 | 0.73 | GAA (0.69) | GAAMAPTMMEACESMYD3 | |
| SCHEMBL29831598 | 0.73 | GAA (0.69) | GAAMAPTMMEACESMYD3 | |
| SCHEMBL26613545 | 0.73 | PRCP (0.38) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000060-A1 | NOVEL COMPOUNDS | AstraZeneca UK Limited (GB) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999002528-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1999-01-21 | — | — | WO | disclosed |