Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.47 |
| ▸ | PTGIR | P43119 | 4/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7949263 | 0.80 | PTGER4 (0.58) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL8129795 | 0.78 | PTGER4 (0.52) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL8136149 | 0.75 | PTGER4 (0.47) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL7960001 | 0.72 | PTGIR (0.78) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL7964177 | 0.71 | PTGIR (0.68) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL7964171 | 0.71 | PTGIR (0.73) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL7961287 | 0.70 | PTGER4 (0.61) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL7949540 | 0.70 | PTGER4 (0.69) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL7959999 | 0.69 | PTGER4 (0.70) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL7961753 | 0.68 | PTGER4 (0.69) | PTGER4PTGIRPTGER1PTGER3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0989975-A1 | OXAZOLE COMPOUNDS USEFUL AS PGE2 AGONISTS AND ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |
| WO-1998055468-A1 | OXAZOLE COMPOUNDS USEFUL AS PGE2 AGONISTS AND ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-10 | — | — | WO | disclosed |