Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.58 |
| ▸ | PTGIR | P43119 | 4/20 | 0.58 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.58 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 10/20 | 0.43 |
| ▸ | RXRA | P19793 | 5/20 | 0.41 |
| ▸ | RXRB | P28702 | 4/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 3/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8129795 | 0.91 | PTGER4 (0.52) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL7959999 | 0.90 | PTGER4 (0.70) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL7964265 | 0.84 | RXRA (0.52) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL7960001 | 0.82 | PTGIR (0.78) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL8129797 | 0.80 | PTGER4 (0.47) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL7961287 | 0.79 | PTGER4 (0.61) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL7949540 | 0.79 | PTGER4 (0.69) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL7964177 | 0.79 | PTGIR (0.68) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL7964171 | 0.79 | PTGIR (0.73) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL7961753 | 0.78 | PTGER4 (0.69) | PTGER4PTGIRPTGER1PTGER3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245790-B1 | ANTIINFLAMMATORY AGENTS; GASTROINTESTINAL DISORDERS; SKN DISORDERS; BONE DISORDERS; MUSCLE RELAXANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-12 | — | — | US | disclosed |