Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2246036 | 0.95 | GRIN2B (0.43) | GRIN2BGRIN2CHPGDJAK3USP2 | |
| SCHEMBL630080 | 0.92 | GRIN2B (0.38) | GRIN2BGRIN2CHPGDJAK3USP2 | |
| SCHEMBL6642949 | 0.85 | HPGD (0.36) | GRIN2BGRIN2CHPGDJAK3USP2 | |
| SCHEMBL15922454 | 0.84 | GRIN2B (0.39) | GRIN2BGRIN2CHPGDJAK3USP2 | |
| SCHEMBL14956788 | 0.83 | GRIN2B (0.38) | GRIN2BGRIN2CHPGDJAK3USP2 | |
| SCHEMBL14956785 | 0.83 | GRIN2B (0.38) | GRIN2BGRIN2CHPGDJAK3USP2 | |
| SCHEMBL705581 | 0.83 | GRIN2B (0.38) | GRIN2BGRIN2CHPGDJAK3USP2 | |
| SCHEMBL2981422 | 0.82 | JAK3 (0.48) | GRIN2BGRIN2CHPGDJAK3USP2 | |
| SCHEMBL1839800 | 0.82 | GRIN2B (0.38) | GRIN2BGRIN2CHPGDJAK3USP2 | |
| SCHEMBL29619416 | 0.82 | GRIN2B (0.40) | GRIN2BGRIN2CHPGDJAK3USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000030-A1 | PIPERIDINE OLIGOMERS AND COMBINATORIAL LIBRARIES THEREOF | Phytera Symbion ApS (DK) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999003832-A1 | PIPERIDINE OLIGOMERS AND COMBINATORIAL LIBRARIES THEREOF | PHYTERA SYMBION APS (DK) | 1999-01-28 | — | — | WO | disclosed |