SCHEMBL8130146

SCHEMBL8130146

CCn1nccc1OC(=O)c1ccc2c(c1C)C(Cl)C(C)(C)CS2(=O)=O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCK P35557 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8127340 0.83
SCHEMBL8137523 0.83
SCHEMBL8129289 0.77 SMN1; SMN2 (0.35)
SCHEMBL8131190 0.69
SCHEMBL8136245 0.68 TSHR (0.38)
SCHEMBL8940919 0.67 SMN1; SMN2 (0.32)
SCHEMBL12636788 0.67 L3MBTL1 (0.33) GCK
SCHEMBL10671194 0.66 KMT2A (0.51)
SCHEMBL8544405 0.66
SCHEMBL8544408 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6159904-A Pyrazole derivatives IDEMITSU KOSAN CO., LTD. (JP) 2000-12-12 US disclosed
EP-0970956-A1 PYRAZOLE DERIVATIVES IDEMITSU KOSAN COMPANY LIMITED (JP) 2000-01-12 EP disclosed