Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SPHK2 | Q9NRA0 | 11/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 8/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876100 | 0.82 | NPC1 (0.51) | SPHK2SPHK1AOC3CYP1A2POLB | |
| SCHEMBL8875583 | 0.81 | NPC1 (0.56) | SPHK2SPHK1AOC3CYP1A2POLB | |
| SCHEMBL8132486 | 0.78 | CYP2D6 (0.51) | GAAMAPTAOC3CYP1A2CYP3A4 | |
| SCHEMBL8135362 | 0.77 | CYP2D6 (0.50) | GAAMAPTAOC3CYP1A2CYP3A4 | |
| SCHEMBL9173291 | 0.73 | NR1I2 (0.49) | GAAMAPTAOC3CYP3A4CYP2D6 | |
| SCHEMBL8875601 | 0.71 | CYP2D6 (0.53) | GAAMAPTAOC3CYP1A2CYP3A4 | |
| SCHEMBL8136233 | 0.71 | CYP2D6 (0.66) | GAAMAPTAOC3CYP1A2CYP3A4 | |
| SCHEMBL12270837 | 0.71 | S1PR1 (0.64) | MAPTCYP1A2CYP2C9CYP2C19HTT | |
| Hydrochloric Acid SCHEMBL22265365 | 0.71 | SPHK2 (0.59) | GAAMAPTSPHK2SPHK1CYP1A2 | |
| Hydrochloric Acid SCHEMBL22265364 | 0.71 | SPHK2 (0.59) | GAAMAPTSPHK2SPHK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566199-B1 | 1,2,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | SANOFI SA (FR) | 2000-03-01 | — | — | EP | disclosed |
| US-5643929-A | TREATMENT OF PICORNAVIRAL OR RHINOVIRUS AND CHEMICAL INTERMEDIATES | SANOFI WINTHROP, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5464848-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1995-11-07 | — | — | US | disclosed |
| US-5349068-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1994-09-20 | — | — | US | disclosed |