Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TOP1 | P11387 | 2/20 | 0.38 |
| ▸ | TOP2A | P11388 | 3/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8132040 | 0.95 | KCNH2 (0.46) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL8130731 | 0.89 | KCNH2 (0.61) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL8572307 | 0.89 | KCNH2 (0.61) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9022897 | 0.86 | KCNH2 (0.54) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9380356 | 0.86 | KCNH2 (0.67) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9023119 | 0.86 | KCNH2 (0.56) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| Hydrochloric Acid SCHEMBL8131737 | 0.85 | KCNH2 (0.66) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9023449 | 0.84 | KCNH2 (0.53) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL8132039 | 0.84 | KCNH2 (0.56) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL8565082 | 0.84 | KCNH2 (0.56) | KCNH2ALDH1A1POLBOPRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401623-B1 | Process for the preparation of 7-(3-amino- and 3-aminomethyl-1-pyrrolidinyl)-3-quinolinonecarboxylic and -naphthyridinonecarboxylic acids | BAYER AG (DE) | 2000-01-26 | — | — | EP | disclosed |
| EP-0401623-A1 | Process for the preparation of 7-(3-amino- and 3-aminomethyl-1-pyrrolidinyl)-3-quinolinonecarboxylic and -naphthyridinonecarboxylic acids | BAYER AG (DE) | 1990-12-12 | — | — | EP | disclosed |