Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.67 |
| ▸ | TOP1 | P11387 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8131737 | 0.99 | KCNH2 (0.66) | KCNH2TOP1ALDH1A1POLBOPRM1 | |
| SCHEMBL9665917 | 0.94 | KCNH2 (0.58) | KCNH2TOP1ALDH1A1POLBOPRM1 | |
| SCHEMBL9023119 | 0.91 | KCNH2 (0.56) | KCNH2TOP1ALDH1A1POLBOPRM1 | |
| SCHEMBL9022897 | 0.89 | KCNH2 (0.54) | KCNH2TOP1ALDH1A1POLBOPRM1 | |
| SCHEMBL9376511 | 0.89 | KCNH2 (0.54) | KCNH2TOP1ALDH1A1POLBOPRM1 | |
| SCHEMBL9380854 | 0.89 | KCNH2 (0.53) | KCNH2TOP1ALDH1A1POLBOPRM1 | |
| SCHEMBL8112090 | 0.88 | KCNH2 (0.82) | KCNH2TOP1ALDH1A1POLBOPRM1 | |
| SCHEMBL10443783 | 0.88 | ALDH1A1 (0.64) | KCNH2TOP1ALDH1A1POLBOPRM1 | |
| SCHEMBL8195801 | 0.88 | ALDH1A1 (0.64) | KCNH2TOP1ALDH1A1POLBOPRM1 | |
| SCHEMBL10443397 | 0.88 | ALDH1A1 (0.64) | KCNH2TOP1ALDH1A1POLBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236673-B1 | Process for quinoline-3-carboxylic acid antibacterial agents | WARNER LAMBERT CO (US) | 1994-07-13 | — | — | EP | claimed |
| EP-0235589-B1 | USE OF QUINOLONE AND NAPHTHYRIDINE ANTIBIOTICS FOR THE MANUFACTURE OF OPHTHALMIC MEDICAMENTS | WARNER-LAMBERT COMPANY (US) | 1992-10-28 | — | — | EP | claimed |
| EP-0198678-B1 | A PROCESS FOR PREPARING SUBSTITUTED QUINOLINE-3-CARBOXYLIC ACIDS | WARNER-LAMBERT COMPANY (US) | 1991-08-21 | — | — | EP | claimed |
| EP-0200307-B1 | IMPROVED PROCESS FOR PRODUCTION OF QUINOLINE-3-CARBOXYLIC ACID ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1989-12-20 | — | — | EP | claimed |