Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 19/20 | 0.63 |
| ▸ | MTNR1B | P49286 | 18/20 | 0.63 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8125047 | 0.91 | MTNR1A (0.61) | MTNR1AMTNR1B | |
| SCHEMBL8128784 | 0.88 | MTNR1A (0.60) | MTNR1AMTNR1B | |
| SCHEMBL8118135 | 0.87 | MTNR1A (0.63) | MTNR1AMTNR1BANO1 | |
| SCHEMBL8126605 | 0.86 | MTNR1A (0.65) | MTNR1AMTNR1B | |
| SCHEMBL8133947 | 0.85 | MTNR1A (0.58) | MTNR1AMTNR1B | |
| SCHEMBL8132541 | 0.84 | MTNR1A (0.46) | MTNR1AMTNR1B | |
| SCHEMBL8131451 | 0.83 | MTNR1A (0.63) | MTNR1AMTNR1B | |
| SCHEMBL8118138 | 0.82 | MTNR1A (0.64) | MTNR1AMTNR1B | |
| SCHEMBL8132270 | 0.81 | MTNR1A (0.61) | MTNR1AMTNR1B | |
| SCHEMBL8132419 | 0.80 | MTNR1A (0.63) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147110-A | MELATONINERGIC AGENTS; SLEEP, EATING, CENTRAL NERVOUS SYSTEM, AND CARDIOVASCULAR DISORDERS | ADIR ET COMPAGNIE (FR) | 2000-11-14 | — | — | US | disclosed |
| EP-0926145-A1 | Napthalene compounds, method for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-06-30 | — | — | EP | disclosed |