Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31445160 | 1.00 | KDM4E (0.52) | KDM4EHTTLMNAL3MBTL1PSMB5 | |
| SCHEMBL27900720 | 0.86 | PTGS2 (0.51) | KDM4EHTTLMNAL3MBTL1PSMB5 | |
| SCHEMBL12984806 | 0.86 | PTGS2 (0.51) | KDM4EHTTLMNAL3MBTL1PSMB5 | |
| SCHEMBL2331560 | 0.85 | PSMB5 (0.49) | KDM4EHTTLMNAL3MBTL1PSMB5 | |
| SCHEMBL25657551 | 0.85 | SMN1; SMN2 (0.50) | KDM4EHTTLMNAL3MBTL1PSMB5 | |
| SCHEMBL27883399 | 0.85 | EPHX2 (0.50) | KDM4EHTTLMNAL3MBTL1PSMB5 | |
| SCHEMBL8861463 | 0.85 | EPHX2 (0.50) | KDM4EHTTLMNAL3MBTL1PSMB5 | |
| SCHEMBL12983786 | 0.85 | KDM4E (0.50) | KDM4EHTTLMNAL3MBTL1PSMB5 | |
| SCHEMBL12983738 | 0.84 | KDM4E (0.52) | KDM4EHTTLMNAL3MBTL1PSMB5 | |
| SCHEMBL28495150 | 0.84 | SMN1; SMN2 (0.52) | KDM4EHTTLMNAL3MBTL1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020366-A | Butyric acid matrix metalloproteinase inhibitors | WARNER-LAMBERT COMPANY (US) | 2000-02-01 | — | — | US | disclosed |
| US-5756650-A | COMPOSITION COMPRISING POLYAMIC ACID, CURE ACCELERATOR SELECTED FROM GROUP CONSISTING OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AMINO ACID COMPOUND, AROMATIC COMPOUND HAVING TWO OR MORE HYDROXYL GROUPS | KABUSHIKI KAISHA TOSHIBA (JP) | 1998-05-26 | — | — | US | disclosed |