Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701763 | 0.79 | ALDH1A1 (0.54) | SLC1A3ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL8134776 | 0.79 | ALDH1A1 (0.54) | SLC1A3ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9046891 | 0.79 | ALDH1A1 (0.54) | SLC1A3ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL3679108 | 0.77 | ACACB (0.43) | HTT | |
| SCHEMBL1895598 | 0.77 | SLC1A3 (0.57) | SLC1A3ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL1849668 | 0.75 | SLC1A3 (0.56) | SLC1A3ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9267275 | 0.74 | ACACB (0.62) | SLC1A3ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL23240006 | 0.74 | SLC1A3 (0.54) | SLC1A3ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL1833147 | 0.74 | SLC1A3 (0.58) | SLC1A3ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL1837626 | 0.74 | SLC1A3 (0.58) | SLC1A3ALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738269-B1 | PIPERIDINE DERIVATIVES WITH PAF ANTAGONIST ACTIVITY | URIACH & CIA SA J (ES) | 2000-04-26 | — | — | EP | disclosed |