Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | YWHAG | P61981 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3253115 | 0.89 | MAPT (0.51) | CYP1A2CYP3A4CYP2C19PMP22TSHR | |
| SCHEMBL8103430 | 0.82 | FFAR4 (0.56) | FFAR4TDP1FFAR1PPARAPPARG | |
| SCHEMBL29110921 | 0.82 | TDP1 (0.61) | CYP3A4TSHRL3MBTL1APPTDP1 | |
| SCHEMBL27665939 | 0.81 | TSHR (0.44) | TSHRL3MBTL1POLBAPPYWHAG | |
| SCHEMBL28327983 | 0.81 | TSHR (0.51) | CYP1A2CYP3A4CYP2C19BLMPMP22 | |
| SCHEMBL11331529 | 0.79 | HDAC3 (0.50) | TSHRL3MBTL1POLBAPPYWHAG | |
| SCHEMBL27905842 | 0.78 | POLB (0.47) | CYP1A2CYP2C19TSHRL3MBTL1POLB | |
| SCHEMBL8132571 | 0.77 | FFAR4 (0.52) | L3MBTL1FFAR4TDP1FFAR1PPARA | |
| SCHEMBL10932955 | 0.77 | PPARD (0.43) | CYP1A2CYP3A4CYP2C19PMP22L3MBTL1 | |
| SCHEMBL11228865 | 0.77 | TAAR1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850232-B1 | BENZOTHIAZOLONE DERIVATIVES | ASTRA PHARMA PROD (GB) | 2000-03-15 | — | — | EP | disclosed |