Hydrochloric Acid

Hydrochloric Acid

SCHEMBL813276

CCCCC1=Cc2ccccc2C1[Zr+2].[Cl-].[Cl-]

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 1/20 0.33
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
TSHR P16473 1/20 0.36
CYP2C19 P33261 1/20 0.36
BCHE P06276 1/20 0.33
LMNA P02545 1/20 0.33
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
HTR5A P47898 1/20 0.31
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL27948578 0.97 CYP3A4 (0.36) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
Bromide SCHEMBL27932887 0.97 CYP3A4 (0.36) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
Fluoride Ion SCHEMBL27948723 0.97 CYP3A4 (0.36) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
Hydrochloric Acid SCHEMBL7636246 0.95 CYP2D6 (0.40) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
Hydrochloric Acid SCHEMBL7636653 0.94 CYP2D6 (0.42) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
Hydrochloric Acid SCHEMBL812474 0.90 CYP11B1 (0.33) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
Fluoride Ion SCHEMBL27948626 0.86 CYP3A4 (0.32) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
Bromide SCHEMBL27203208 0.86 HTR2A (0.32) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
Iodide SCHEMBL27932942 0.86 CYP3A4 (0.32) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
Hydrochloric Acid SCHEMBL29651804 0.82 CYP11B1 (0.37) CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115141298-A Polyolefin resin and process for producing the same DL化学株式会社 2022-10-04 CN disclosed
CN-111454389-B Catalyst composition for polymerization of polyolefin, method for preparing polyolefin, and polyolefin resin DL化学株式会社 2022-07-15 CN disclosed
CN-111454389-A Catalyst composition for polymerization of polyolefin, process for producing polyolefin, and polyolefin resin 大林产业株式会社 2020-07-28 CN disclosed
US-8957158-B2 Impact resistant LLDPE composition and films made thereof BASELL POLYOLEFINE GMBH (DE) 2015-02-17 US disclosed
US-8846188-B2 Impact resistant LLDPE composition and films made thereof Basell Poliolefine GmbH (DE) 2014-09-30 US disclosed
EP-2344551-B1 IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF BASELL POLYOLEFINE GMBH (DE) 2014-05-28 EP disclosed
CN-103509060-A Metallocene compound, catalyst composite containing metallocene compound and olefin polymerization method using metallocene compound DAELIM IND CO LTD 2014-01-15 CN disclosed
EP-2361281-B1 IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF BASELL POLYOLEFINE GMBH (DE) 2012-11-21 EP disclosed
US-20110230629-A1 Impact Resistant LLDPE Composition and Films Made Thereof BASELL POLYOLEFINE GMBH (DE) 2011-09-22 US disclosed
US-20110223406-A1 Impact Resistant LLDPE Composition and Films Made Thereof BASELL POLYOLEFINE GMBH (DE) 2011-09-15 US disclosed
US-20110212283-A1 Impact Resistant LLDPE Composition and Films Made Thereof BASELL POLYOLEFINE GMBH (DE) 2011-09-01 US disclosed
EP-2361281-A1 IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF Basell Polyolefine GmbH (DE) 2011-08-31 EP disclosed
EP-2344551-A1 IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF Basell Polyolefine GmbH (DE) 2011-07-20 EP disclosed
EP-2337811-A1 IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF Basell Polyolefine GmbH (DE) 2011-06-29 EP disclosed
EP-2326678-A1 IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF Basell Polyolefine GmbH (DE) 2011-06-01 EP disclosed
WO-2010034461-A1 IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF BASELL POLYOLEFINE GMBH (DE) 2010-04-01 WO disclosed
WO-2010034508-A1 IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF BASELL POLYOLEFINE GMBH (DE) 2010-04-01 WO disclosed
WO-2010034464-A1 IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF BASELL POLYOLEFINE GMBH (DE) 2010-04-01 WO disclosed
WO-2010034520-A1 IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF BASELL POLYOLEFINE GMBH (DE) 2010-04-01 WO disclosed
WO-2010034463-A1 IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF BASELL POLYOLEFINE GMBH (DE) 2010-04-01 WO disclosed