Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8133138 | 1.00 | PPARG (0.57) | PPARGPPARA | |
| SCHEMBL8141923 | 0.91 | KCNH2 (0.50) | PPARGPPARA | |
| SCHEMBL8141922 | 0.91 | KCNH2 (0.50) | PPARGPPARA | |
| SCHEMBL10366704 | 0.90 | HPGD (0.61) | PPARGPPARA | |
| SCHEMBL10364994 | 0.90 | HPGD (0.61) | PPARGPPARA | |
| SCHEMBL10364971 | 0.90 | HPGD (0.61) | PPARGPPARA | |
| SCHEMBL8133143 | 0.89 | PPARG (0.55) | PPARGPPARA | |
| SCHEMBL6966781 | 0.83 | PPARG (0.52) | PPARGPPARA | |
| SCHEMBL6966778 | 0.83 | PPARG (0.52) | PPARGPPARA | |
| SCHEMBL9316520 | 0.82 | PIM1 (0.45) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605228-A1 | Thiazolidinedione derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1994-07-06 | — | — | EP | claimed |
| EP-0605228-B1 | Thiazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-03-01 | — | — | EP | disclosed |
| US-5489602-A | HYPOGLYCEMIC AND HYPOLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-06 | — | — | US | disclosed |
| EP-0605228-A1 | Thiazolidinedione derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1994-07-06 | — | — | EP | disclosed |