Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 8/20 | 0.56 |
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8133157 | 1.00 | REN (0.56) | RENCTSKPSMB5MAPK1 | |
| SCHEMBL8141216 | 0.90 | REN (0.56) | RENCTSK | |
| SCHEMBL8142067 | 0.89 | REN (0.54) | RENCTSKMAPK1 | |
| SCHEMBL8138671 | 0.86 | PTPN1 (0.51) | RENCTSKPSMB5 | |
| SCHEMBL8133513 | 0.86 | REN (0.47) | RENPSMB5MAPK1 | |
| SCHEMBL8140184 | 0.86 | REN (0.53) | RENCTSK | |
| SCHEMBL8140187 | 0.86 | REN (0.53) | RENCTSK | |
| SCHEMBL16462832 | 0.85 | REN (0.51) | RENCTSK | |
| SCHEMBL16462833 | 0.85 | REN (0.51) | RENCTSK | |
| SCHEMBL8142583 | 0.84 | PTPN1 (0.49) | RENCTSKPSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6018020-A | VIRICIDES WHICH ARE PROTEASE INHIBITORS AGAINST HEPATITIS C AND HEPATITIS G | HOFFMAN-LA ROCHE INC. (US) | 2000-01-25 | — | — | US | disclosed |