Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.48 |
| ▸ | TUBB | P07437 | 4/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127820 | 0.85 | TUBB4A (0.51) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8130608 | 0.84 | MEN1 (0.55) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL18889754 | 0.83 | RECQL (0.58) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL18889752 | 0.83 | RECQL (0.58) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8124723 | 0.82 | MAPT (0.50) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6431367 | 0.78 | TUBB4A (0.43) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6431369 | 0.78 | TUBB4A (0.43) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8398768 | 0.78 | TUBB4A (0.55) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8398771 | 0.78 | TUBB4A (0.55) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9096892 | 0.77 | NQO1 (0.48) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0645382-B1 | COUMARIN DERIVATIVE AND USE THEREOF | MORINAGA MILK INDUSTRY CO LTD (JP) | 2000-07-12 | — | — | EP | disclosed |
| EP-0645382-A1 | COUMARIN DERIVATIVE AND USE THEREOF | MORINAGA MILK INDUSTRY CO., LTD. (JP) | 1995-03-29 | — | — | EP | disclosed |