Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19036886 | 0.83 | ALDH1A1 (0.30) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL10455610 | 0.74 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10NPSR1GLO1 | |
| SCHEMBL10084560 | 0.72 | NPSR1 (0.63) | ALDH1A1LMNAHSD17B10NPSR1GLO1 | |
| SCHEMBL8137656 | 0.69 | — | — | |
| SCHEMBL19133543 | 0.69 | — | — | |
| SCHEMBL26414003 | 0.69 | NPSR1 (0.44) | ALDH1A1LMNAHSD17B10NPSR1GLO1 | |
| SCHEMBL334984 | 0.68 | NPSR1 (0.60) | ALDH1A1LMNAHSD17B10NPSR1GLO1 | |
| SCHEMBL15684410 | 0.68 | — | — | |
| SCHEMBL11857889 | 0.68 | HCAR2 (0.50) | ALDH1A1LMNAHSD17B10NPSR1GLO1 | |
| SCHEMBL622054 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0814078-B1 | Process for the preparation of polyenic esters and -acids | HOFFMANN LA ROCHE (CH) | 2000-04-05 | — | — | EP | claimed |
| US-5986113-A | MULTISTAGE PROCESS FOR FORMING PIGMENTS | ROCHE VITAMINS INC (US) | 1999-11-16 | — | — | US | claimed |
| EP-0814078-A1 | Process for the preparation of polyenic esters and -acids | F. HOFFMANN-LA ROCHE AG (CH) | 1997-12-29 | — | — | EP | claimed |
| EP-0814078-B1 | Process for the preparation of polyenic esters and -acids | HOFFMANN LA ROCHE (CH) | 2000-04-05 | — | — | EP | disclosed |
| US-5986113-A | MULTISTAGE PROCESS FOR FORMING PIGMENTS | ROCHE VITAMINS INC (US) | 1999-11-16 | — | — | US | disclosed |
| US-5763651-A | CONDENSATION OF UNSATURATED ETHERS IN THE PRESENCE OF LEWIS ACIDS | ROCHE VITAMINS INC. (US) | 1998-06-09 | — | — | US | disclosed |
| EP-0814078-A1 | Process for the preparation of polyenic esters and -acids | F. HOFFMANN-LA ROCHE AG (CH) | 1997-12-29 | — | — | EP | disclosed |
| EP-0814078-A1 | Process for the preparation of polyenic esters and -acids | F. HOFFMANN-LA ROCHE AG (CH) | 1997-12-29 | — | — | EP | disclosed |