Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 6/20 | 0.47 |
| ▸ | MMP9 | P14780 | 4/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119927 | 0.91 | MEN1 (0.38) | MEN1KMT2ACYP2C9MMP2MMP9 | |
| SCHEMBL8120021 | 0.90 | BACE1 (0.41) | MEN1KMT2ACYP2C9MMP2MMP9 | |
| SCHEMBL8129240 | 0.89 | KMT2A (0.37) | MEN1KMT2ACYP2C9MMP2MMP9 | |
| SCHEMBL8121322 | 0.88 | S1PR4 (0.41) | MEN1KMT2ACYP2C9MMP2MMP9 | |
| SCHEMBL8121259 | 0.88 | KMT2A (0.36) | MEN1KMT2ACYP2C9MMP2MMP9 | |
| SCHEMBL8120585 | 0.87 | KDM4E (0.36) | MEN1KMT2ACYP2C9MMP2MMP9 | |
| SCHEMBL8130937 | 0.86 | KDM4E (0.48) | KMT2AMMP2MMP9MMP1MMP3 | |
| SCHEMBL8126519 | 0.86 | AGTR2 (0.39) | MEN1KMT2ACYP2C9MMP2MMP9 | |
| SCHEMBL8119786 | 0.86 | KMT2A (0.35) | MEN1KMT2ACYP2C9MMP2MMP9 | |
| SCHEMBL8130474 | 0.86 | PTAFR (0.36) | MEN1KMT2ACYP2C9MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543858-B1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND APPLICATION | BRITISH BIOTECH PHARM (GB) | 2000-12-20 | — | — | EP | claimed |