Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 6/20 | 0.36 |
| ▸ | CCR2 | P41597 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8134651 | 1.00 | LMNA (0.42) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL8131175 | 1.00 | LMNA (0.42) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL8131174 | 1.00 | LMNA (0.42) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL8131173 | 1.00 | LMNA (0.42) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL6442624 | 0.84 | LMNA (0.36) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL8132391 | 0.84 | LMNA (0.36) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL8124553 | 0.84 | LMNA (0.36) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL8133043 | 0.84 | LMNA (0.36) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL8132393 | 0.84 | LMNA (0.36) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL23071549 | 0.78 | IDH1 (0.40) | LMNANR1I2ABCB11ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0989162-A1 | THERMOPLASTIC RESIN COMPOSITION, WATER-BASED COMPOSITION, HEAT-SENSITIVE PRESSURE-SENSITIVE ADHESIVE, AND HEAT-SENSITIVE SHEET | Daicel Chemical Industries, Ltd. (JP) | 2000-03-29 | — | — | EP | disclosed |