Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11475484 | 0.85 | FNTA (0.41) | GRIK1GRIK2FNTAFNTBMEN1 | |
| SCHEMBL3092195 | 0.83 | FNTA (0.63) | GRIK1GRIK2FNTAFNTBKDM4E | |
| SCHEMBL11811520 | 0.82 | FNTA (0.39) | GRIK1GRIK2FNTAFNTBMEN1 | |
| SCHEMBL7694807 | 0.80 | LMNA (0.39) | GRIK1GRIK2FNTAFNTBMEN1 | |
| SCHEMBL14815638 | 0.80 | FNTA (0.76) | FNTAFNTBMEN1KMT2AKDM4E | |
| SCHEMBL11549341 | 0.79 | FNTA (0.79) | FNTAFNTBMEN1KMT2AKDM4E | |
| SCHEMBL11551174 | 0.79 | FNTA (0.79) | FNTAFNTBMEN1KMT2AKDM4E | |
| SCHEMBL11549345 | 0.79 | FNTA (0.79) | FNTAFNTBMEN1KMT2AKDM4E | |
| SCHEMBL11551176 | 0.79 | FNTA (0.79) | FNTAFNTBMEN1KMT2AKDM4E | |
| SCHEMBL28755811 | 0.76 | FNTA (0.35) | GRIK1GRIK2FNTAFNTBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6049010-A | Method of preparing 3-(3-methyl-2-buten-1-yl)-2,4-pentanedione and related dicarbonyl compounds | LOYOLA UNIVERSITY OF CHICAGO (US) | 2000-04-11 | — | — | US | claimed |
| US-6049010-A | Method of preparing 3-(3-methyl-2-buten-1-yl)-2,4-pentanedione and related dicarbonyl compounds | LOYOLA UNIVERSITY OF CHICAGO (US) | 2000-04-11 | — | — | US | disclosed |
| US-6049010-A | Method of preparing 3-(3-methyl-2-buten-1-yl)-2,4-pentanedione and related dicarbonyl compounds | LOYOLA UNIVERSITY OF CHICAGO (US) | 2000-04-11 | — | — | US | disclosed |
| US-3998872-A | PREPARATION OF UNSATURATED CARBONYL COMPOUNDS | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1976-12-21 | — | — | US | disclosed |