Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18250743 | 0.76 | L3MBTL1 (0.36) | CYP3A4CYP2C9CYP2D6CYP1A2GABRA1 | |
| SCHEMBL8128909 | 0.76 | CYP3A4 (0.33) | CYP3A4CYP2C9CYP2D6CYP1A2GABRA1 | |
| SCHEMBL13274743 | 0.75 | ADORA2A (0.38) | CYP3A4CYP2C9CYP2D6CYP1A2GABRA1 | |
| SCHEMBL18250721 | 0.70 | CYP3A4 (0.34) | CYP3A4CYP2C9CYP2D6CYP1A2GABRA1 | |
| SCHEMBL18250740 | 0.68 | CYP3A4 (0.35) | CYP3A4CYP2C9CYP2D6CYP1A2GABRA1 | |
| SCHEMBL11109615 | 0.67 | CYP3A4 (0.31) | CYP3A4CYP2C9CYP2D6CYP1A2GABRA1 | |
| SCHEMBL28012784 | 0.65 | CYP19A1 (0.30) | CYP11B1CYP11B2 | |
| SCHEMBL19171559 | 0.64 | — | — | |
| SCHEMBL3635030 | 0.63 | HRH4 (0.31) | CYP3A4CYP2C9CYP1A2GABRA1GABRB2 | |
| SCHEMBL27832085 | 0.63 | ADORA2A (0.35) | CYP3A4CYP2C9CYP1A2GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008128986-A1 | UREA DERIVATIVES AS GLUTAMINYL CYCLASE INHIBITORS | PROBIODRUG AG (DE) | 2008-10-30 | — | — | WO | disclosed |