Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 3/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5348805 | 0.97 | CNR2 (0.47) | PIM1PIM3CNR2BRD4DYRK1A | |
| SCHEMBL5109147 | 0.89 | BCHE (0.39) | PIM1PIM3CNR2BRD4IDO1 | |
| SCHEMBL25962881 | 0.88 | TLR7 (0.49) | PIM1PIM3CNR2 | |
| SCHEMBL1951717 | 0.87 | PIM1 (0.44) | PIM1PIM3CNR2DYRK1ASTING1 | |
| SCHEMBL5364616 | 0.85 | TLR7 (0.48) | PIM1PIM3CNR2DYRK1A | |
| SCHEMBL1952878 | 0.84 | CNR2 (0.44) | PIM1PIM3CNR2DYRK1ASTING1 | |
| SCHEMBL5346497 | 0.84 | TLR7 (0.48) | PIM1PIM3CNR2DYRK1AIDO1 | |
| SCHEMBL8136997 | 0.83 | PIM1 (0.44) | PIM1PIM3CNR2BRD4DYRK1A | |
| SCHEMBL5118893 | 0.83 | TLR7 (0.41) | PIM1PIM3CNR2IDO1 | |
| SCHEMBL8127843 | 0.82 | BRD4 (0.48) | PIM1PIM3CNR2BRD4DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069149-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | TERUMO KABUSHIKI KAISHA (JP) | 2000-05-30 | — | — | US | disclosed |
| EP-0894797-A1 | NOVEL AMIDE DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | TERUMO KABUSHIKI KAISHA (JP) | 1999-02-03 | — | — | EP | disclosed |