Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5349379 | 0.97 | CNR2 (0.44) | PIM1PIM3PDPK1CCNB2PRKCB | |
| SCHEMBL4343039 | 0.89 | BCHE (0.40) | CA12CA1CA2CA9CNR2 | |
| SCHEMBL5354727 | 0.83 | PDPK1 (0.44) | PIM1PIM3PDPK1CCNB2PRKCB | |
| SCHEMBL8135396 | 0.83 | PIM1 (0.47) | PIM1PIM3DRD2CNR2IDO1 | |
| SCHEMBL25962881 | 0.80 | TLR7 (0.49) | PIM1PIM3CNR2 | |
| SCHEMBL5350633 | 0.80 | PDPK1 (0.45) | PDPK1CCNB2PRKCBCDK1LYN | |
| SCHEMBL5348805 | 0.80 | CNR2 (0.47) | PIM1PIM3DRD2CNR2IDO1 | |
| SCHEMBL1951717 | 0.79 | PIM1 (0.44) | PIM1PIM3DRD2CNR2IDO1 | |
| SCHEMBL5364616 | 0.77 | TLR7 (0.48) | PIM1PIM3CNR2DYRK1A | |
| SCHEMBL5118893 | 0.77 | TLR7 (0.41) | PIM1PIM3CNR2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069149-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | TERUMO KABUSHIKI KAISHA (JP) | 2000-05-30 | — | — | US | disclosed |
| EP-0894797-A1 | NOVEL AMIDE DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | TERUMO KABUSHIKI KAISHA (JP) | 1999-02-03 | — | — | EP | disclosed |