Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8135658 | 1.00 | RAB9A (0.50) | RAB9AMAPTSMN1; SMN2NPC1CA1 | |
| SCHEMBL8135655 | 1.00 | RAB9A (0.50) | RAB9AMAPTSMN1; SMN2NPC1CA1 | |
| SCHEMBL29365442 | 0.87 | CA1 (0.62) | RAB9AMAPTSMN1; SMN2NPC1CA1 | |
| SCHEMBL79637 | 0.87 | CA1 (0.62) | RAB9AMAPTSMN1; SMN2NPC1CA1 | |
| SCHEMBL79638 | 0.87 | CA1 (0.62) | RAB9AMAPTSMN1; SMN2NPC1CA1 | |
| SCHEMBL29374751 | 0.78 | MAPT (0.63) | RAB9AMAPTSMN1; SMN2NPC1MAOB | |
| SCHEMBL1781200 | 0.78 | MAPT (0.63) | RAB9AMAPTSMN1; SMN2NPC1MAOB | |
| SCHEMBL1781201 | 0.78 | MAPT (0.63) | RAB9AMAPTSMN1; SMN2NPC1MAOB | |
| SCHEMBL31464870 | 0.78 | MAPT (0.63) | RAB9AMAPTSMN1; SMN2NPC1MAOB | |
| Guanidine SCHEMBL7166541 | 0.78 | CA1 (0.51) | RAB9AMAPTSMN1; SMN2NPC1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049682-A1 | OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION | Versicor, Inc. (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999037630-A1 | OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION | VERSICOR, INC. (US) | 1999-07-29 | — | — | WO | disclosed |