Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 12/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8136676 | 1.00 | KDM4E (0.34) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL8137717 | 0.94 | KDM4E (0.37) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL8137718 | 0.90 | KDM4E (0.38) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL8122410 | 0.87 | KDM4E (0.41) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL8127648 | 0.86 | MEN1 (0.45) | HTTSMN1; SMN2MAOB | |
| SCHEMBL8130151 | 0.86 | MEN1 (0.45) | HTTSMN1; SMN2MAOB | |
| SCHEMBL8129094 | 0.80 | MEN1 (0.48) | HTTSMN1; SMN2MAOB | |
| SCHEMBL8129379 | 0.80 | MEN1 (0.48) | HTTSMN1; SMN2MAOB | |
| SCHEMBL8133034 | 0.77 | VCAM1 (0.38) | SMN1; SMN2 | |
| SCHEMBL8129321 | 0.77 | VCAM1 (0.38) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006108-A1 | 3-Hydroxy-2(1H)-pyridinone or 3-hydroxy-4(1H)-pyridinone derivatives useful as reactive oxygen species (ROS) scavengers | Cerebrus Pharmaceuticals Limited (GB) | 2000-06-07 | — | — | EP | disclosed |