Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 16/20 | 0.78 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.78 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.78 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6589245 | 0.95 | OPRL1 (0.79) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL4915159 | 0.95 | OPRL1 (0.85) | OPRL1OPRM1OPRK1SIGMAR1TMEM97 | |
| SCHEMBL4918269 | 0.92 | OPRL1 (0.76) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL4918155 | 0.90 | OPRL1 (0.82) | OPRL1OPRM1OPRK1SIGMAR1OPRD1 | |
| SCHEMBL4921253 | 0.88 | OPRL1 (0.81) | OPRL1OPRM1OPRK1OPRD1 | |
| J-113,397 SCHEMBL875219 | 0.88 | OPRL1 (1.00) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL4921256 | 0.88 | OPRL1 (0.81) | OPRL1OPRM1OPRK1OPRD1 | |
| J-113,397 SCHEMBL4920647 | 0.88 | OPRL1 (1.00) | OPRL1OPRM1OPRK1OPRD1 | |
| J-113,397 SCHEMBL6586337 | 0.88 | OPRL1 (1.00) | OPRL1OPRM1OPRK1OPRD1 | |
| J-113,397 SCHEMBL29623041 | 0.88 | OPRL1 (1.00) | OPRL1OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990653-A1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |