J-113,397

J-113,397

SCHEMBL875219

CCn1c(=O)n([C@@H]2CCN(CC3CCCCCCC3)C[C@H]2CO)c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 18/20 1.00
OPRM1 P35372 11/20 1.00
OPRK1 P41145 6/20 1.00
OPRD1 P41143 2/20 0.40
DRD2 P14416 1/20 0.39
DRD4 P21917 1/20 0.39
DRD3 P35462 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
J-113,397 SCHEMBL29623055 1.00 OPRL1 (1.00) OPRL1OPRM1OPRK1OPRD1DRD2
J-113,397 SCHEMBL12918433 1.00 OPRL1 (1.00) OPRL1OPRM1OPRK1OPRD1DRD2
J-113,397 SCHEMBL1946862 1.00 OPRL1 (1.00) OPRL1OPRM1OPRK1OPRD1DRD2
J-113,397 SCHEMBL29623041 1.00 OPRL1 (1.00) OPRL1OPRM1OPRK1OPRD1DRD2
J-113,397 SCHEMBL4920647 1.00 OPRL1 (1.00) OPRL1OPRM1OPRK1OPRD1DRD2
J-113,397 SCHEMBL6586337 1.00 OPRL1 (1.00) OPRL1OPRM1OPRK1OPRD1DRD2
J-113,397 SCHEMBL4920487 0.99 OPRL1 (0.98) OPRL1OPRM1OPRK1OPRD1DRD2
J-113,397 SCHEMBL16752513 0.99 OPRL1 (0.98) OPRL1OPRM1OPRK1OPRD1DRD2
J-113,397 SCHEMBL4920476 0.99 OPRL1 (0.98) OPRL1OPRM1OPRK1OPRD1DRD2
SCHEMBL4919683 0.92 OPRL1 (0.85) OPRL1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115296253-B Self-recovery overvoltage and undervoltage protection circuit 湖南科技大学 2025-05-09 CN claimed
CN-117978139-A Reset delay circuit 安徽熙泰智能科技有限公司 2024-05-03 CN claimed
US-20240050559-A1 METHOD OF MAKING VIRUS-LIKE PARTICLE ICOSAVAX, INC. 2024-02-15 US claimed
CN-116234567-A Method for assembling two-component virus-like particles Icosavax股份有限公司 2023-06-06 CN claimed
EP-4161943-A2 METHOD OF MAKING VIRUS-LIKE PARTICLE Icosavax, Inc. (US) 2023-04-12 EP claimed
CN-115833837-A High-speed Flash-SAR hybrid analog-to-digital converter 大连理工大学 2023-03-21 CN claimed
CN-115296253-A Self-recovery type over-voltage and under-voltage protection circuit 湖南科技大学 2022-11-04 CN claimed
EP-3500572-B1 CYTISINE DERIVATIVES FOR THE TREATMENT OF ADDICTION UNIV BRISTOL (GB) 2022-10-26 EP claimed
CN-114758687-B Self-adaptive Cache access circuit and implementation method thereof 南京低功耗芯片技术研究院有限公司 2022-09-02 CN claimed
CN-114758687-A Self-adaptive Cache access circuit and implementation method thereof 南京低功耗芯片技术研究院有限公司 2022-07-15 CN claimed
CN-111950565-B Abstract picture image direction identification method based on feature fusion and naive Bayes 山西大学 2022-05-20 CN claimed
CN-111265663-B Application of orphanin enkephalin receptor specific antagonist in preparation of arrhythmia treatment drug 郭政 2022-04-22 CN claimed
US-7557088-B2 Methods and compositions for treating conditions NEOPRO LABS, LLC (US) 2009-07-07 US claimed
WO-2026087396-A1 BIOBASED ADHESIVE COMPOSITION, METHOD FOR OBTAINING SAME AND USE THEREOF AS ADHESIVE Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (FR) 2026-04-30 WO disclosed
US-12606828-B2 Aptamers for use in the treatment of Coronaviridae infections APTA Therapeutics GmbH (DE) 2026-04-21 US disclosed
WO-2026079292-A1 GLASS, NEAR-INFRARED ABSORPTION CUT-OFF FILTER, AND SOLID-STATE IMAGING ELEMENT AGC株式会社 2026-04-16 WO disclosed
US-7300947-B2 N-dihydroxyalkyl-substituted 2-oxo-imidazole derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 2007-11-27 US disclosed
US-20070015792-A1 N-dihydroxyalkyl-substituted 2-oxo-imidazole derivatives MSD K.K. (JP) 2007-01-18 US disclosed
US-20070015792-A1 N-dihydroxyalkyl-substituted 2-oxo-imidazole derivatives MSD K.K. (JP) 2007-01-18 US disclosed
WO-2005004896-A1 NOP RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PARKINSON’S DISEASE UFPEPTIDES S.R.L. (IT) 2005-01-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070015792-A1 N-dihydroxyalkyl-substituted 2-oxo-imidazole derivatives OPRL1, OPRK1, GPR119 OPRL1 1/4885OPRM1 10/4885OPRK1 2/4885
US-12606828-B2 Aptamers for use in the treatment of Coronaviridae infections DNTT, TPT1, TEKT1 OPRL1 3379/4885OPRM1 2839/4885OPRK1 3313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.