Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3840724 | 0.77 | SLC22A2 (0.31) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9785088 | 0.76 | — | — | |
| SCHEMBL9639400 | 0.74 | — | — | |
| SCHEMBL4055790 | 0.69 | CYP2C9 (0.41) | CYP2C9EPHX2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL546127 | 0.67 | CYP2C9 (0.39) | CYP2C9EPHX2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1497395 | 0.65 | LMNA (0.43) | CYP2C9GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL14645140 | 0.65 | GRIN2D (0.39) | CYP2C9EPHX2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL812661 | 0.65 | CYP2C9 (0.38) | CYP2C9EPHX2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL3849728 | 0.64 | CYP2C9 (0.36) | CYP2C9GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL2807432 | 0.64 | LMNA (0.46) | CYP2C9GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0362771-B1 | Use of photochromic substances | RODENSTOCK OPTIK G (DE) | 2000-05-31 | — | — | EP | disclosed |
| US-5637709-A | Photochromatic substances | OPTISCHE WERKE G. RODENSTOCK (DE) | 1997-06-10 | — | — | US | disclosed |
| US-5608065-A | ADAMANTANEOSPIRO-HETEROAROMATIC PYRANS | OPTISCHE WERKE G. RODENSTOCK (DE) | 1997-03-04 | — | — | US | disclosed |
| EP-0362771-A1 | Photochromic substances | Optische Werke G. Rodenstock (DE) | 1990-04-11 | — | — | EP | disclosed |
| WO-1990003379-A1 | PHOTOCHROMIC SUBSTANCES | OPTISCHE WERKE G. RODENSTOCK (DE) | 1990-04-05 | — | — | WO | disclosed |