Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8136460 | 1.00 | NPC1 (0.34) | NPC1RAB9AMAPTMEN1ALDH1A1 | |
| SCHEMBL10402861 | 0.89 | NPC1 (0.32) | NPC1RAB9AMAPTMEN1ALDH1A1 | |
| SCHEMBL10402859 | 0.89 | NPC1 (0.32) | NPC1RAB9AMAPTMEN1ALDH1A1 | |
| SCHEMBL9328922 | 0.84 | NPC1 (0.42) | NPC1RAB9AMAPTMEN1ALDH1A1 | |
| SCHEMBL8121798 | 0.82 | MEN1 (0.40) | NPC1RAB9AMAPTMEN1ALDH1A1 | |
| SCHEMBL10430090 | 0.82 | NPC1 (0.34) | NPC1RAB9AMAPTMEN1ALDH1A1 | |
| SCHEMBL8121794 | 0.81 | MEN1 (0.39) | NPC1RAB9AMAPTMEN1ALDH1A1 | |
| SCHEMBL8121792 | 0.81 | MEN1 (0.39) | NPC1RAB9AMAPTMEN1ALDH1A1 | |
| SCHEMBL10402863 | 0.80 | NPC1 (0.32) | NPC1RAB9AMAPTMEN1ALDH1A1 | |
| SCHEMBL9143711 | 0.79 | MEN1 (0.41) | NPC1RAB9AMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525057-B1 | ANTIMICROBIAL QUINOLONYL LACTAMS | PROCTER & GAMBLE PHARMA (US) | 2000-06-14 | — | — | EP | disclosed |
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |