Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3028010 | 0.69 | TSHR (0.44) | DDAH1L3MBTL1ALDH1A1TP53TNKS2 | |
| SCHEMBL3027998 | 0.68 | GAA (0.39) | DDAH1MEN1GAAKMT2A | |
| SCHEMBL11298020 | 0.66 | EGFR (0.47) | EGFRL3MBTL1ALDH1A1MEN1GAA | |
| SCHEMBL29477327 | 0.65 | TAAR1 (0.56) | ALDH1A1KMT2AARP2RX7HPGD | |
| SCHEMBL2090458 | 0.65 | TAAR1 (0.56) | ALDH1A1KMT2AARP2RX7HPGD | |
| SCHEMBL25047048 | 0.65 | L3MBTL1 (0.44) | DDAH1L3MBTL1ALDH1A1GAATP53 | |
| SCHEMBL11210876 | 0.65 | TAAR1 (0.46) | ALDH1A1KMT2AARHPGD | |
| SCHEMBL6548002 | 0.65 | TAAR1 (0.46) | ALDH1A1KMT2AARHPGD | |
| SCHEMBL4119398 | 0.64 | EGFR (0.74) | EGFRDDAH1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL11200954 | 0.63 | TAAR1 (0.54) | ALDH1A1KMT2AARP2RX7HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994877-A1 | IMIDAZOPYRIMIDINES AND IMIDAZOPYRIDINES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | Du Pont Pharmaceuticals Company (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001454-A1 | IMIDAZOPYRIMIDINES AND IMIDAZOPYRIDINES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-01-14 | — | — | WO | disclosed |